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Director Medicinal Chemistry




Our client, MercachemSyncom is one of the largest chemistry CROs in Europe. With more than 300 highly trained and dedicated chemists, MercachemSyncom provides a range of services to support small-molecule drug discovery and development projects for biopharmaceutical companies in the USA, Europe, and Japan. Their key areas of expertise include (parallel) synthetic chemistry, medicinal chemistry, process R&D and GMP manufacturing.

After Mercachem and Syncom joined their forces in 2017, the resulting MercachemSyncom Group became the premier European mid-sized CRO offering innovative best-in-class chemistry solutions. MercachemSyncom Group has a proven track record of almost 30 years supporting leading pharma and biotechnology companies with innovative and complex medicinal chemistry programs. Starting as a chemistry service provider, the Group has transformed into an integrated drug discovery CRO offering innovative chemistry, medicinal chemistry, library synthesis, early process research services and cGMP manufacturing services to accelerate the drug discovery and development process in a flexible and cost-effective way. Furthermore, the Group has developed independently novel chemical matter in a number of areas, including CDK8 and Tankyrase which will be further developed in milestone-based partnerships. MercachemSyncom is recognized as a world leader in chiral chemistry with a strong focus on chiral resolution technology. With close to 275 chemists (> 50% PhD) working in state-of-the-art laboratory facilities, the Group serves many pharmaceutical and biotech companies throughout the world and is renowned for its high-quality services and problem-solving capabilities.

MercachemSyncom is an international company and this is also reflected by the diverse nationalities of their employees.

MercachemSyncom is based at three locations:
Mercachem BV, Kerkenbos, Nijmegen (NL)
Syncom BV, Zernike Park, Groningen (NL)
Mercachem Prague (CZ), GMP kilolab facility

MercachemSyncom’s company ethos of open communication and shared knowledge requires an open-doors policy. This is reflected in the design of their buildings, which facilitates close working relationships.


As part of the increasing demand for their services in medicinal chemistry, we are currently looking for skilled and enthusiastic

Director Medicinal Chemistry
to lead the medicinal chemistry activities at the Syncom site in Groningen

As a senior member of their Medicinal Chemistry group, you will be overseeing all small molecule drug discovery projects on different target classes pertaining to different disease areas at the Syncom site. You will have responsibility for the quality and delivery of medicinal chemistry applied in lead finding and lead optimization projects. You will be accountable for solving complex chemistry problems, unfolding conclusive structure-activity and structure-property relationships, within agreed timelines. You will also contribute to molecular design through current expertise or development in those areas.

Profiel kandidaat

• Ph.D., Post Doctoral Fellowship in Synthetic Organic or Medicinal Chemistry.
• Minimum of ten year’s practical Medicinal Chemistry laboratory and
management experience in the pharmaceutical or related industry.
• Previous supervisory experience in a pharmaceutical company.
• Previous experience in leadership of Medicinal Chemistry projects, especially in Hit-
to-Lead and Lead Optimisation Phases, leading to the delivery of Pre-Clinical
• Experience in at least two different therapeutic areas.


An exciting position in a dynamic organization with an attractive primary and secondary employment conditions.


Marjo Lucker | Senior Consultant / Process manager
+31 (0) 6 – 13 56 19 88 | lucker@themagroup.nl

Marije Hoogendoorn | Senior Recruitment Specialist
+31 (0) 6 – 23 13 51 18 | hoogendoorn@themagroup.nl

Tagcloud Director Medicinal Chemistry

projectmanagement - medicinal chemistry - small molecule drug discovery - syncom - mercachem - groningen - synthetic organic chemistry
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Merowingerplatz 1


BioVille, Agoralaan
Building A bis

Pivot Park Kloosterstraat 9 
5349 AB OSS


Odiliastraat 92
5401 ZZ UDEN

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